I'd like to have a party of 4 with every character some day. :O I only played first as a Siren. Lilith was powerful but could easily flee+heal. Maya is too much of a support role to play solo, lol. ;-;
Me and my buddy played the first one with me as brick and him as Mordecai. So when the second one came out, I was Salvador, and he was Zero. I have to admit, I like playing Salvador more. Fits my style better. But he's only good if you have a partner to back you up.