Please don't say that only humans are left cause then you're saying a 100% Pokemon are dead then its pointless searching for them.
Also; if Pokemon don't exist, then how can there be wild encounters, trainer battles, and gym battles?
In such a game wild encounters are impossible.
Tell me, if trainers all around the world are using this technology then :
1]Why is the word "new invention" used?
2]What exactly are you investigating?
Also; it isn't really logical for you to find Pokemon DNA lying around in grass and caves just for you to pick up. Especially to get passed "obstacles"
It's a good plot but you'll have to fix up a lot of stuff before it can be used in a game.