Region I'd say Kanto, being my favorite because I like the towns in the area and honestly from what I saw in the anime series in Kanto, there are a lot of places I'd love to see and explore. It'd be a dream come true.
Hometown Hm, Viridian City probably, I was thinking of saying Pallet town, but I'm not really keen on living in any small towns, even in real life. I like decent sized cities with a lot of people and places to see in.
Partner Pokemon I'd have a Evee because I'd love, and always wanted a Umbreon.
Wouldn't give my Pokemon a nickname. Guess I'd have to see what kind of personality my Pokemon would have.