I can remember a few... like I used my only Masterball on Zekrom in White, and in SoulSilver I had a full team of Pokemon, and then my brain went stupid when I got everyone's health down really low. I went to the Elite Four... and I saved... and I challenged them... and I lost... and I reloaded... and I went to rest... here's the worst part: I saved again, because a happy saver is a happy player

, and then my DS died. While it was saving. I cried for a while after that.