Yeah my friends will tease me about my awkwardness and random stuff all the time, which I don't mind at all.
As for more serious teasing, I've had my fair share. As a kid I was that weird kid who never talked to anyone, didn't stand out, whatever. I did obviously take offense, but as I got older I learned to deal with it. When I came out as trans, there was definitely more teasing. Not as much as I initially thought, which is good, but still teasing nonetheless. But now it has no effect on me, it's just really sad when people try to tease others.