Honestly, I absolutely loathed DMC4 with every inch of my being from start to finish. I tried with all of my might to find one thing about that game that I actually liked and fell short of anything even remotely redeemable in the end. My favorite part of that game was knowing that I'll never have to pick it up and play it again after finishing it but I digress.
Protags for Dante's Inferno other than Dante? Gotta admit there's really nobody in general who comes to mind on that one atm.
Thought the main story of GOW ended with GOW 3.