Hinata was doing her best in part one, she just didn't really get any real screentime or development after the Chunin exam arc. At that point she wasn't my favourite character in the series but she was pretty great comic relief.
The line was Itachi commenting on Sasuke's knowledge of snakes, he'd been studying them as he thought it'd help him against Orochimaru. The internet loved it as it's an obvious anagram.
Oh yes, anybody can change the topic. I don't want to alienate people