I'm not a massive fan of these, but I do have fond memories of watching Never Mind the Buzzcocks back when Simon Amstell and Bill Bailey were still there. The level of consistency on that show at that time was greater than most other panel shows of its ilk. That, and it was hella funny and introduced the world to the craziness that was Amy Winehouse before we realised how screwed up she unfortunately was. It lost a lot of its steam when Amstell, and then Bailey, departed, unfortunately. But those few years where it all clicked were glorious. And most of them are on YouTube as well!