It's looks like a few people are overestimating the size of 50 acres. It's actually not all that big- about 0.2 km2 or 0.1 mi2 (roughly the size of a large shopping mall). If you want an example of a 5 acre area, you can take a look at this picture.
Still, if I had that amount of land, I think I'd like to build a Pokemon Day Care/Breeding center. That would be more than enough room for a bunch of Pokemon to play and roam around, and I'd still get the opportunity to interact with numerous species of Pokemon and their trainers.