Huh.. I never really cared about the gender. Really the only time in my life where I cared about the gender of a Pokémon was, when I got a male Luvdisc in Sapphire because that was somewhat special since Luvdisc has a 75% change of being female.
I really don't care if my Pokémon is male or female. Of course it's weird to find a male Lopunny or a female Machoke but who gives.. If anything it's even better because it's funny.