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Old April 15th, 2013 (12:58 PM).
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Kanzler Kanzler is offline
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For some positive breaking biotech news:

Researchers at the Massachusetts General Hospital have created laboratory-grown rat kidneys that function when transplanted into rats according to a study published online yesterday in the medical journal Nature Medicine.
The kidneys were capable of urine production and excretion without blood clots in both the laboratory and inside living rats. The researchers were able to create the functional kidneys by using a donor kidney and using a detergent to remove the rats' kidney cells, then used new cells to cause the kidney to grow around the remaining "scaffolding," the natural protein-based structure of the kidney that remained after washing the kidney.
These kidneys would also be of the patient's tissue avoiding issues of organ rejection and would increase the pool of kidneys available for human transplant.
The researchers incubated the kidneys in a specialized oven for 12 days to mimic the insides of a rat. The researchers reported that these kidneys produced urine at 23% of the normal levels of properly working kidneys.
The lead researcher of the study published in Nature Medicine, Dr. Harald C. Ott, says this partial functionality is enough, saying, "If you're on haemodialysis then kidney function of 10% to 15% would already make you independent of hemodialysis. It's not that we have to go all the way."
The techniques developed by Ott and the team of researchers still have to be further researched before it can be applied for use in humans. When it comes time for use in humans, Ott says that pigs' kidneys would be used as the templates for making human-usable kidneys.
Ott said, "You’d take a kidney matrix off the shelf. Then in an ideal world, you’d take cells from that patient and create a kidney on demand."
Roughly 100,000 patients in the United States need an immediate kidney transplant, with 500,000 more on dialysis.

I researched artificial organs for Grade 12 bio sometime back, but the articles were about artificial trachea - that don't really do much. This is a kidney. It filters bloods and excretes urine. In 3 years we go from trachea to functioning organs. Now it's not entirely perfect and there's some tweaking to do, but what do you guys think? Pretty good use of stem cell tech eh?

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Old April 15th, 2013 (4:44 PM).
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gimmepie gimmepie is offline


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This is impressive, really,really impressive and useful. This technology (for want of a better word) will one day be saving human lives and countering the need to wait years upon years for a transplant. I just hope it doesn't get commercialised so only the rich are able to stay alive.

Crazy religious and conservative political groups are going to go mad about this, just putting that out there.

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