I'll play it like I played the previous games the first go around. I'll talk to everybody, explore every house, talk to every garbage can for free items, and battle every Trainer.
I kinda hope there isn't a Habitat List this time around though. Don't get me wrong, it was my favorite new feature, but the completionist in me won't leave an area until I've captured every Pokemon there. Needless to say, it slowed down my Black 2 playthrough considerably, with all those shaking grasses and muttering profanity under my breath when yet ANOTHER Audino begs to get slaughtered. On the bright side, I was quite overleveled by the time it mattered, so win-win?