In a world where all Pokémon replace the real world equivalents they have, I think we'd be in danger. I mean, imagine going for a nice swim at a random lake and seeing beams of ice and torrents of water shot in all directions. Basically any human would be putting their life in quite a lot of danger by walking into any sort of wild habitat. "Oh this jungle is quite lovely wait what's th-" *killed by a hyperbeam*
I'd love it if the pokémon were somehow stripped of their superpowers and were basically funky looking animals, though.