i must say, it's nice to see some new kind of artwork such as a comic! i've never had an idea or the skills to create one.
Wow, these are pretty cool.
One thing I would say is look at the human anatomy. For example, on the first page, when collecting the Pokéballs, his hand kinda... bends? And his other hand looks like some kind of alien hand developed to impale its victims. Anyway, it's not that bad, my analogies seem kinda extreme but you get the point. Just try and look at you own hand and others' hands as they pick stuff up and do stuff, and do that with the whole body too. Some practise sketches never hurt, and you can put them here too. Another small thing I noticed is that your character's jaw seems a little wonky. Try and make it a little sharper.
If you wanna go for the anime-style face, a sharp jaw-line is essential. Yours seem just a tad too... chubby? No, not quite that but perhaps try and refine them a little. I do realise this is done with pixel art, and is hard to achieve, and I admire what you've got so far, so don't take this thinking I think it's crap, not at all! You're good, and I wanna help you get even better ;)
i completely agree with Aiden. when i first saw your drawings, i think you have the comic look down with the sketchiness. i like how you create shadows and depth from using different line techniques. what first bothered me about the characters was the fact that their face is somewhat boxy. i feel like the face is much more smoother. also, the hand in the first post did bother me too. i remember when i took drawing class, that was one of the first things we did! we had to stare at our hand and draw it! (such a pain!) i always have difficulty drawing people, so you are already much more advanced at drawing than i am! if you were to go more for an anime style, i would definitely try to get the glossy eye down. it seems you have somewhat of a glossy eye, but it's not as depth as the other parts of the comics. i must say, i hope you keep drawing this comic and creating more. i do really like your style!