Not at all. I have a chronic pain condition and before I gave up diagnosing exactly what was wrong and decided to just treat the symptoms, I had sooo many doctors appointments that I became pretty immune to them. I suppose maybe if I had a new more serious issue crop up that would probably change, but for general things, I know how the appointments go and I've been there so many times that basically nothing makes me nervous. I think the only time I've been nervous for an appointment in the last long, long while is when I had to switch family doctors because I wasn't really sure if my new one would prescribe my restricted meds as easily, but it wasn't a problem and I'm back to my regular carefree appointments.
I get slightly nervous when I have to get blood drawn but mostly just because my veins are notoriously hard to find and the actual procedure tends to get me a little queasy, so I usually anticipate a couple false starts before they manage to get it done and it's not uncommon to need a few vials so it's usually just kind of a miserable experience. Back in university there was this little old lady who worked part time at the clinic I went to and I'd always go for bloodwork on the days she worked because she was SO good at it. Always one and done with her. But now that I get bloodwork much less frequently, it's a mixed bag as to what kind of experience I'll have. So I guess I'm kind of nervous when this happens but usually it's just resigned annoyance at what's likely to come lol.