I'm really looking forward to what is likely the new "Xeno" title, as well as the Fire Emblem X Shin Megami Tensei game. Both of those are on my "Must Buy" list. Then there's Soul Hackers, which I'll be getting. God Mode will be ten bucks, I'll definitely be getting that (at some point, at least, not at launch). Those are just some off of the top of my head- oh, but probably the game I'm looking forward to most that may or may not come out this year is Ace Attorney 5, and if not that, Professor Layton vs. Phoenix Wright.
But what I'm REALLY looking forward to this year is E3. It has a lot of potential...though last year's did as well, and it was the worst yet. I'm hopeful, though, and the recent Nintendo direct (as well as the announcement that Super Smash Bros 4 will be there) have enforced that hope. It will either be the worst E3 yet, or the best E3 in years, and I'm hoping for the latter.