Sasuke was turned into a loner by "the times" and the entire series is about fighting that. Can you think of one main enemy in the series that wasn't initially a good kid? (Zabuza and Haku, Gaara, Sasuke, Pain, *the guy in the mask who I won't say as I don't think some of you are manga readers*, Madara) There is Orochimaru as well but we don't really know much about him yet, he might just be a sociopath but he probably has his reasons)
So yes, once he realises he's being stupid and he's much better off going home I'm sure his interest in vaginas will go up. Also I seem to remember him having 2 goals, Killing Itachi and resurrecting his clan.