Guest123_x1
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In the Generation I games that I have played (before finding out about the item cloning glitch), I saved the Master Ball for Mewtwo, as had been suggested by many game guides and walkthroughs-however on my first full playthrough of Yellow, I wasted it on a Farfetch'd after getting frustrated over it breaking out of my Great Balls. I don't recall ever using my Master Ball in any of the Generation II games.