1. Jessie: Many view Jessie as being a monstrous *****, but there is more to her than meets the eye. Though she can act harsh and selfish, she also has a kinder and more sensitive side to her personality. Overall, she is a complex and interesting character with multiple layers. Considering she was badly hurt by others and experienced numerous disappointments in her past, her behavior also makes sense. I cannot help but feel empathy for her.
Furthermore, I like her strength of will, independence, and determination. She also provides the show with great comedy, especially through her interaction with James.
2. James: I love James' character. He is kind hearted, gentle, sensitive, loyal, and intelligent. He also has a great sense of humor and provides the series with outstanding comical relief. The suffering he had to endure in his childhood also makes me feel empathy for him. Furthermore, not only is his character design hot, but his voice was sexy as hell when Eric Stuart did it.
3. Meowth: Meowth is fun. I like his sarcasm and wise-cracks, not to mention his Giovanni fantasies are humorous. Like Jessie and James, his painful past also makes me feel empathy for him.
4. Conway: I like that creepy nerd. He is hilarious.
5. Lyra: I enjoy Lyra. She is a tough girl who always comes out on top. Her one-sided crush on Dane (do not tell me she does not want her. "Dane" is a pet name :D) and relationship with Khorey are also entertaining.
6. Khorey: Because he is the ultimate submissive. Even Brock has ordered him around :)