As I'm playing through the game I have to say it's very well done, however, I managed to find few bugs.
First one is in Poppy town, there's a guy asking you to deliver cookies to his girlfriend. After you deliver it to her and come back to him, the game crashes as he is giving you the reward.
Next one is in Zesia in the house of nature changing president Sarah. If you click on the bookshelf (third one), it sends you to Palmer Island. I thought that it's secret area, cleared it but was stuck on an island being unable to go back (the boat that was supposed to come for me didn't come) forced to start playing from the beginning.
Last one I found is as you are trying to enter Arlong's gym without going to hospital to talk to Arlong, there's a green haired guy standing in your way and if you tal to him, instead him turning you turn and stay like that permanently, which results in being unable to leave area because you get stuck after leaving.
Otherwise i think this is fantastic game and really enjoying it, hope it gets finished. Wish you good luck.
By the way, is there way to open the door with guy standing in front of it talking about losing key on route 2?