It's been a while since I played the game so I'm a bit hazy on the details of the overall ending, and I'm not going to mince words since, at least in terms of Infinite, this is clearly going to be a spoiler-heavy zone with no holds-barred.
...That said, this isn't going to be some rant. At the time I could have done one, but this'll be incredibly brief. It was a well-thought out ending in terms of the overall story, but at the same time, after a point it was rather predictable (for instance, Comstock's identity and the "twist" at the end) and slightly confusing. Giving them the girl and wiping away the debt is essentially what sets the plot in motion, happening before the plot of the game even starts (and to the player, at the beginning of the game before you go to the fair- that's a clever bit of direction there). This is all well and good, but the resolution to the story, the solution that Elizabeth comes up with to prevent the game from happening, is eliminating the choice altogether. What's strange about this, however, is that once the choice is eliminated and DeWitt wakes up from his desk, he goes screaming in surprise with the idea that his daughter might actually be in the room next to him.
This makes no sense. DeWitt never gave anybody "the girl". There was no reason that she would be gone. And one could try to argue that he remembers things from the events of the game, but that can't happen, because there doesn't exist a single timeline where the gave the girl away as payment for the debt. This always bothered me, as it really felt like they through away all that they built up in the last few moments before we arrive at the Title Screen. Of course, even if you forsake that, there's still the fact that Elizabeth still has a ruthless, cold-hearted murderer of a father, one that has undergone any sort of redemption or introspection, and is ultimately doomed to be raised by him.
That...again, is a very small sliver of my thoughts on it, and I'd probably have to see it again (or play the game again) to draw out my thoughts, but that's what stuck out to me most, at least (and it seems I minced quite a few words).
