Mew and Mewtwo are equel in power (on anime, dunno about games) and they have every move (again on anime) so on anime, Mew and Mewtwo are definatelly the best, but i'm not sure on the game, cus on game, the weakest can be strongest lol, Mewtwo/Mew faints on game, on anime they are indestructable, and also on game Mew doesn't obey, so it depends if you're going on about anime or game, since they will have a different answer