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I just beat Red. I got the game 9 AM last Sunday, so it took me 6 days, 12 hours and 21 minutes to complete. In-game, I spent 37 hours and 30 minutes.
YEEEEEEAH
Pokémon does not have a definite ending; you play and level beyond the final bosses. For games that have different difficulties, one should be able to beat the game on a lower difficulty and then move up. I haven't played Metroid or Fire Emblem, but I've played Kingdom Hearts, and the difficulty...
I think they should just keep it at 3 years. I don't think they would change it just because the real-world timeline differs, the game can be its own canon with its own timeline.
No, you cannot exchange Mystery Gifts. Actually, I don't think you can do that with any Nintendo-distributed Wonder Cards so far... But I believe the option exists in Pokésav.
GTS Cloning is much more accurate if you use the light on your router. Once it starts flickering, you can turn off the DS. I had to start doing this because it was never the same amount of clock turns each time, anywhere from 6 to 10 :/