MySims Party.
We only have that because we just got the Wii (along with an even worse-looking game, which we sold for MySims Party), and my parents wanted us to get a cheap multiplayer game that everyone could enjoy. Eh, not really that awesome, if you ask me.
Nintendogs.
Cute at first, but gets boring after a while. I think it's the fact that I have to keep feeding/cleaning them, like, every day or else they'll get stinky. It just isn't worth my money (which is why I ended up selling both for an imported Pokemon Platinum XD).
Sonic and the Secret Rings.
No. Just...no. I prefer old school Sonic, tyvm.
Runescape.
Wtf? Seriously.
Animal Crossing.
I just don't like a lot of non-violent games :X Harvest Moon is probably the only exception. OK, Harvest Moon, and, to a certain extent (though I sold all the games related to it), Hamtaro. Unless you count rolling into another hamster "violent" XD
Kirby: Squeak Squad.
Don't get me wrong, I love Kirby and practically all the games I've ever owned that starred him (Air Ride ftw!). But seriously, I completely beat Squeak Squad in less than 24 hours of me getting the game. I could never do that with Nightmare in Dreamland, Amazing Mirror, etc. I sold this game a bit later on XD
...
That's all I have on the list for now.