Definitely worth picking up if you can get a good deal for 'em. My boyfriend is totally crazy for the Defenders, even that weird 2011 "maybe it happened, maybe it didn't" thing lol, so he'd be the person to ask.
I'm ever so slightly spread out. I absolutely adore Fables (pretty much anything Willingham does, actually), New 52 Batman, and The Walking Dead, so I can't say I'm Marvel exclusive.
But when it comes to superheroes, Marvel all the way x100 <3