Well, i have one Idea (but it may not be good... at all...). It could be like a classic, lovely, trainer Rp except... In the future (cue dramatic music)
Something like Kanto/Johto/etc. Fallout 3ish (if you played the game). Thieves run rabid, supplies are tough to get, but society still "functions" and gyms are still run (but only by new people obviously). Goal: To go to the top while trying to survive.
And Rpers could choose their future, or how they will achieve their goal (Will they work hard and battle to gain money, or steal stuff, or take contracts offered, or poach pokemon?)
That or a Pokemon Poacher RP where you are a Ranger stopping Poachers in various locations.
Watdaya think?