Man, I love that show. It's the kind of series you just kick back and have good laugh. Nothing serious, just good crazy fun. (Every series gets a little predicable overtime wouldn't ya say?)
What I love about Bobobo-Bo-Bobobo most is how it admits to being crazy and pointless: breaking the fourth wall, killing it, burying it in the trash then defiling its grave, its over-exaggeration of certain aspects (more noticeable in the manga like blood loss) and how it parodies every possible cliché there is, like sudden (plot-driven) power-ups, tragic back stories, mysterious characters, situations that would run 15-50+ episodes and settling it in only a matter of minutes or in a very "WTF" manner.
Though it's a series not for the over-serious or those who like to make logic out of everything there ARE a lot of cultural jokes. I'm giving the series credit for simply making fun of the fact it's an English translation of a Japanese anime at points.
In short, Bobobo rocks.