First off, I really hate what they did to Misty.
Misty was cool because she was a girl that did something. Unlike many co-starring girls in anime that has a guy as a main character, Misty actually used her pokemon and battled and looked tough on occasion. She was sometimes hinted as a possible love interest, but she was never made to serve just that purpose.
Then the Orange Islands came around, and Misty got kinda... boring. She still did things though, and her attitude was still there mostly.
Then came Johto, and it all went to hell. XD I mean, this didn't just happen to Misty, it happened to Brock too. Heck even Ash started to get boring! I mean, most episodes centered around developing people we would only see for one episode and never again, and not the actual main characters. Brock and Misty were merely background, there to comment on pokemon moves like some sort of underpaid sports commentators. There were a few times when the old Misty shone through the boring, new one, but those were sparce. I was almost glad when she left, because they had just made her so painful to watch. She was my favorite character.
So I voted "yes" on the poll. But I want it known that my "yes" vote comes with requirements. If Misty is ever brought back, they need to show her off as the tomboy she was, and not the sappy girl she turned into. T_T
It would be interesting to see if she would flirt with Ash though... they seem to have been hinting towards a Misty/Tracey thing in Chronicles. o.o Not that I really mind, poor Tracey needs someone to like besides Professor Oak. XD