"Mouse eggs made from skin cells in a dish" - Nature

[Nihilego]

I'd write my own version up but for now I'll just let the journal do the talking.

Editorial: https://www.nature.com/news/mouse-eggs-made-from-skin-cells-in-a-dish-1.20817

Paper: https://www.nature.com/nature/journal/vaop/ncurrent/full/nature20104.html

I lost it when I was reading the paper and saw the pictures of the actual mice at the end of it. Seeing the supposedly healthy mice at ages up to 11 months (bear in mind that lab mice have shorter lifespans compared to wild ones, typically up to ~14 months depending on their background) is pretty amazing. This is obviously huge and raises loads and loads of questions and possibilities. I'll probably chip in some of my own thoughts whenever I've got time but for now, discuss.

 

[Desinishon]

This is just......amazing. C: To accomplished such thing, man that's really insane...

The next advance came in July 2016, when a team led by Yayoi Obata, at the Tokyo University of Agriculture, reported transforming PGCs extracted from mouse foetuses into oocytes (egg cells) without using a live mammal3. Working with Obata, Hayashi and Saitou have now completed the cycle: from skin cells to functional eggs in a dish. With the use of in-vitro fertilization (IVF) techniques, 26 healthy pups were born (some originally from embryonic stem cells and some from reprogrammed skin cells). Hayashi says some of these animals gave birth to a second generation of mice.

I didn't get what they're doing till here...

Although the biologists did not need to implant the PGCs into living mice, they did need to add cells taken from the ovaries of other mouse foetuses — effectively, to create an ovary-like support in which the eggs could grow

This is the Paragraph where I understand how it's done. Like Hayashi stated he is not planning to do do experiment in human eggs but there is always othes.
I don't know much about biology just basic things but I don't think producing functional human cell in lab will be this easy.

"Rats and mice are mammals that share many processes with humans and are appropriate for use to answer many research questions," said Jenny Haliski, a representative for the National Institutes of Health (NIH) Office of Laboratory Animal Welfare.

Over the last two decades, those similarities have become even stronger. Scientists can now breed genetically-altered mice called "transgenic mice" that carry genes that are similar to those that cause human diseases. Likewise, select genes can be turned off or made inactive, creating "knockout mice," which can be used to evaluate the effects of cancer-causing chemicals (carcinogens) and assess drug safety, according to the FBR.

Even after that I can't seem to wrap my head around this but really in near future whenever this happen it will be historic c:

 

[Sektor]

Wow. Science never fails to amuse or entertain! Totally reminded me of that one scene from Blade Runner