Yes, maybe Mario may seem patronising when with Mikey. But he is showing that he cares, and he is in management after all so he's obviously adapting to this with his experience. And have you seen how some of the housemates are getting 'annoyed' at Mikey, for reasons that are not his fault? I think housemates who are willing to help and show that they care are more valued than those who sit back and do nothing. Some of the housemates are rude to Mikey, and show very little patience with him.
And it seems that Sylvia said it herself, she does behave in an immature manor, since she first kept Mikey awake at night with being disruptive, walked off crying, then started throwing herself all over some new guy in the house when she has a boyfriend! You don't expect somebody like that to help Mikey do you?
People like Mario should be respected for their willingness to help. All the other housemates don't help him the same way, either through being scared or just simply being selfish. I hope Mario stays in that house longer than people want him to.
Anyway enough about Mario from me for now. I think Mikey is over looked / ignored a lot in the house. However, Mikey is capable of taking care of himself yes to a certain extent. But remember he is handicapped, so does need some guidance.