I really doubt that the gender different products will carry over outside of Japan. Most likely the cards in these starter decks will either be made into Trainer Kits, or will be incorporated into our B/W sets. (the most likely option)
I'm also going to guess that the first set or two will focus only on B/W Pokemon, since the games themselves are supposedly going to only contain new Pokemon for the first part of the game.
As for changes to the cards themselves, a new look to the cards is almost guaranteed. As for mechanics, I'm actually hoping they don't have 'special' Pokemon like lv. X's or Legends. Since it looks like they're trying to start fresh with the games, that's the best way the TCG can follow suit.