I lost my Leafgreen a couple years ago. Then, last year, when I was buyin' another Leafgreen for my friend, I bought the exact same game that I've lost! :O
I know because my Charizard was named after me. Also, the Cleffable was named <3 Khmer. ;-;
Nothing has ever happened to my games, but I had a friend who went on a water ride with her GBA and her Ruby version in her not waterproof handbag. Her phone, CD player and wallet all got totally wiped out, I thought her mum would go mental!