Let's see, from the Halo series there's the Battle Rifle, the human Sniper Rifle, the SMG, the original Halo: CE pistol and the shotgun. And I'm not even done. There's also a bunch of guns from Mass Effect I love, like the Tempest SMG, the Vindicator Battle Rifle, the Black Widow Sniper Rifle, the Viper Sniper Rifle, the N7 Eagle Pistol, and every last variation of the Omnitool heavy melee. From the Splinter Cell series, I use the Five-Seven Pistol and SC2000 Assault Rifle very often, but nothing beats using the knife in that game. And that's everything off the top of my head. I may come and post again with more of my favorite tools of destruction.