Yes. As an example, I often find myself wondering why the laws of physics are the way they are and not some other way.
Also grass is green because of chlorophyll, a green chemical found in leaves.
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Anyway, have you ever heard of the Shirt Ninja?
What would I like to see in the future? A few things, actually.
1) A trio of ROM hacks [gen1, gen2, gen3] that, aside from the generation, are pretty much identical: You start in Kanto and post-elite four you travel through Johto as it would have been "3 years ago".
2) A demake of Heart Gold / Soul Silver. Possibly using Fire Red as a base.
3) An official Pokémon game, following the standard "gotta catch 'em all" format, but aimed more at the older players.