Garrus Vakarian, Mass Effect Series
How could you not like this guy? He's your right hand man (Turian?) throughout the games, and he's pretty complex as a character. He can seem cold sometimes, but you know that he's always there to pick you up after a loss, or go have a drink with down at the bar. You won't find a better partner throughout the games, and he's my favorite character because of it. I just hope he knows that I'm saving him a seat at the bar once he's finally done calibrating that gun.
Mordin Solus, Mass Effect Series
The doctor that's just as likely to shoot you as he is to heal you. Seriously, when that's the first thing you hear when you're trying to find him, you know you're in for an interesting guy. His mind works so fast, and I always found my conversations with this guy extremely entertaining because of it. Once second you're talking about the genophage, and the next he's singing up and down the lab reciting his number for the musical he was a part of. He was willing to give the ultimate sacrifice to correct his past mistakes, and I stopped playing the game for a week because of it. Mordin and Garrus rounded out my usual party in Mass Effect 2, and for a good reason.
Urdnot Wrex, Mass Effect Series
Okay, last Mass Effect character, I promise. This guy went from a brute for hire to a political mastermind in one game. I always brought Wrex along with Garrus since we needed some extra firepower, and I never expected to actually like his character. His little quips, good problem solving skills, and helpful insight made for a good contrast to his strength and aggression. He went from being this dumb brute, to one of the smartest people in my party. In my eyes, at least. I'm so glad I was able to save him during the first game, and I was very disappointed when I wasn't able to bring him along during the second and third games. At least there was Mordin, but I still missed those little quips that often had me laughing pretty loudly.
Alistar, League of Legends
Even though I don't play the game anymore, Alistar still stands out to me. Not because he was my main, but his lore is what made me interested in him as a character. I wrote a short story expanding upon that, and I always imagined him as someone who tries to keep all of his anger and sadness inside.
Galio, League of Legends
My second main, and I really think he's a sleeping powerhouse. What really made me like him, however, was his lore. It's pretty dang sad, and makes his statement, "I will protect" mean a little bit more. Hopefully Poppy keeps him company, haha.