Normally. It's still easy to play normally if you accept the mechanics and moves for things will have different functions, and leave it at that.
I usually disagree with the notion that gen 1 is an "unplayable glitch fest", as it's commonly referred to. It is what's made of it. If you actively seek out them then it would turn into that, but I still find it easy to casually play through these games without even noticing them.