My relationship with my biological family has always been difficult. My father and I have a very weird sort of relationship - we're civil, but we're not exactly close, and I doubt we ever will be - and my mother is the main antagonistic force in my life; the one who frequently puts me down, chips away at what little self-image I have left, and generally makes me want to kill myself at the worst of times. That's probably the only thing that would satisfy her.
That said, it could be a lot worse. They haven't kicked me out of the house yet - I suspect mother wants to, but father won't let her - and it's not always constant tension. Especially when my brother is away at College. We get on best by staying out of one another's way, and the way they work means that we're only all in the house together from 5pm onwards and all day Sunday. It works out alright.
I don't know anyone on my father's side, but my mother has two younger sisters. Both of them live pretty far away so I rarely get to see them, although I get on reasonably well with the younger one whenever I see her. She was only around 15 when I was born and I used to play with her a lot when I was very young; I've always liked her. My grandparents I used to be very close to, but then they moved to the other side of the country when I was 11, which effectively destroyed our relationship for the majority of my teens and my early twenties...then I grew up a little. We're on good terms now and they're a very comforting presence in my life.
I find it much easier to choose my own family though, and have done so. If I didn't have my family - that I chose, not my biological family - then it's doubtful I would have lived to see the end of last year. I'm a very solitary person, although I honestly can't imagine life without them now.