I own several physical game guides, because I used to collect the hardback ones in particular when I was younger...honestly I probably still would collect them if they made them for games because they were usually very high quality (if they weren't made by Bradygames, anyway...) and very useful as reference material. I hate missing things, but I also hate wasting time. Sidequest markers are not a given in RPGs (although more have them than not these days) and having to talk to *everyone* in an area when they have nothing relevant to say - and sometimes in a specific order! - really gets on my nerves. Guides have always been more of a reassurance tool and checklist for me than anything else: a way of making sure that I haven't missed anything important that I would want to do if I knew about it.
These days I'll go on Gamefaqs if I have a general query about something (usually where to find a particular item) and if I can't find a location I may watch a Youtube video on how to get there if one is available, but it's been quite a while since I used a guide to tell me what to do in a game. They're more for optional side content, at least for me.